Frontispiece: The Potential of Micellar Media in the Synthesis of DNA-Encoded Libraries

Réka Adamik,Dr. Balázs Buchholcz,Dr. Ferenc Darvas,Dr. Gellért Sipos,Dr. Zoltán Novák

DNA-encoded libraries (DELs) have become a widely used technology in drug discovery. The use of micelle-forming surfactants provides new possibilities for synthetic organic chemistry and could be a promising technique for DNA-compatible chemistry as well. This review provides a summary of existing examples of micellar DEL approaches, together with a selection of micellar organic transformations fundamentally suitable for DEL synthesis….

Read the full article: https://chemistry-europe.onlinelibrary.wiley.com/doi/full/10.1002/chem.202103967

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